Wineries & Breweries in Seneca
The most complete and owner-verified listings first — hours, phone, website, services. No pay-to-play.
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Keowee Brewing Company
401 E Main St, Seneca, SC 29678
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Ram Cat Cellars
124 Ram Cat Alley, Seneca, SC 29678
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Two Horse Distillery
1750 Blue Ridge Blvd, Seneca, SC 29672
Of the 3 wineries & breweries listed in Seneca, 3 give a phone number and 2 have a website. The nearest bigger selection is Clemson with 4.
More locations within 30 miles of Seneca
Only 3 locations listed in Seneca itself, so here are the closest ones in nearby towns. Distance is straight-line from Seneca.
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Freehouse Brewery
7.4 mi · 210 E Main St, Walhalla, SC 29691
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CU Lot 23
7.6 mi · Cherry & Perimeter Road, Clemson, SC 29634
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The Wine Emporium
8.7 mi · 1229 Stamp Creek Rd, Salem, SC 29676
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Elkmont Tap & Cellar
8.8 mi · 100 Liberty Dr Unit 3, Clemson, SC 29631
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Clemson Wine Bar
10.3 mi · 149 Thomas Green Blvd, Clemson, SC 29631
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Kite Hill Brewing Co
10.3 mi · 150 Thomas Green Blvd, Clemson, SC 29631-2165
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The Gypsy Wine Bar
10.8 mi · 168 Exchange St, Pendleton, SC 29670
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Swamp Fox Distilling
10.8 mi · 128 Exchange St, Pendleton, SC 29670-1312
Guides for location shoppers
All guides
OwningThe Ultimate Guide to Charcuterie Boards: Styling, Pairings, and Recipes
Learn how to build balanced charcuterie and cheese boards, from festive holiday trees and brunch platters to portable grazing cups and effortless wine pairings.
OwningCrystal Wine Glassware Guide: Types, Brands, Care, and Stemless Styles
A practical guide to selecting, maintaining, and understanding crystal wine glassware, covering traditional stems, modern tumblers, sparkling vessels, and mineral compositions.
BuyingUnderstanding Bold Reds: Dry Wines, Tannin Profiles, and Old Vine Zinfandels
This guide breaks down what makes red wine dry, how tannins shape mouthfeel, what defines a full-bodied Cabernet, and why old vine Zinfandel earns its distinct reputation.
South Carolina statewide, by feature
- Breweries and Beer Gardens in South Carolina196
- Wine Bars in South Carolina108
- Bottle Shops in South Carolina73
- Wineries with Food in South Carolina64
- Wineries and Vineyards in South Carolina60
- Distilleries in South Carolina50
- Wineries with Tastings in South Carolina22
- Dog-Friendly Wineries in South Carolina19
- Winery Tours in South Carolina17
- Wineries with Outdoor Seating in South Carolina16
Nearby in South Carolina
- Clemson4
- Pendleton6
- Salem3
- Sunset2
- Anderson13
- Easley5
- Charleston52
- Greenville42
Good to know about wineries & breweries in Seneca
How many wineries & breweries are there in Seneca?
We list 3 wineries & breweries in Seneca with addresses, and 3 of them with a phone number.
What's the surest way to check hours in Seneca?
Call ahead — 3 of the 3 wineries & breweries here list a number. Hours at independent wineries & breweries shift with seasons and staffing, so a phone call beats any listing, including ours.
What to wear wine tasting?
Smart casual attire is recommended, such as dark clothing to avoid stain visibility and comfortable flat shoes for walking on gravel or lawns. Avoid heavy perfumes as they interfere with the subtle aromas during a tasting. You can browse 3 tasting venues in Seneca, South Carolina, with 3 listed with direct contact details to confirm dress code policies.
What to wear on a wine tour?
Dress in comfortable layers and wear closed-toe flat shoes suitable for cellar floors and outdoor vineyard walking. Bring a light jacket or sweater, as wine cellars are kept cool year-round. Check out 3 wine tour providers in Seneca, South Carolina, including 3 that offer phone assistance for tour planning.