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Wineries & Breweries in Florence, SC

7 locations in and around Florence, South Carolina — call ahead or check hours before the drive — many small wineries and taprooms pour only Thursday through Sunday, and harvest season can change everything.

Florence has about 40,923 residents, which works out to 17 wineries & breweries per 100,000 people. Population: U.S. Census Bureau, 2024 estimate.

Wineries & Breweries in Florence

The most complete and owner-verified listings first — hours, phone, website, services. No pay-to-play.

  1. Southern Hops Brewing Co.

    911 S Sunset Acres Ln, Florence, SC 29501

    Food servedDog friendly
  2. Cru Wine & Tap

    122 W Evans St, Florence, SC 29501

    Food served
  3. Boxwood Distillery

    3914 Hoffmeyer Rd, Florence, SC 29501-9033

  4. Seminar Brewing & Elliott's BBQ Lounge

    551 W Lucas St, Florence, SC 29501

  5. Straw Hat Distillery

    1301 N Douglas St, Florence, SC 29501

  6. Local Motive Brewing

    2519 W Palmetto St, Florence, SC 29501

  7. Grateful Dog Festival

    901-999 State Rd S-21-700, Florence, SC 29501

7locations
17per 100,000 residents
6with a phone
5with a website

Of the 7 wineries & breweries listed in Florence, 6 give a phone number and 5 have a website. The nearest bigger selection is Charleston with 52.

Wineries & Breweries in Florence by feature

Florence 7 locations

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Good to know about wineries & breweries in Florence

How many wineries & breweries are there in Florence?

We list 7 wineries & breweries in Florence with addresses, and 6 of them with a phone number.

What's the surest way to check hours in Florence?

Call ahead — 6 of the 7 wineries & breweries here list a number. Hours at independent wineries & breweries shift with seasons and staffing, so a phone call beats any listing, including ours.

What to wear wine tasting?

Smart casual attire is recommended, such as dark clothing to avoid stain visibility and comfortable flat shoes for walking on gravel or lawns. Avoid heavy perfumes as they interfere with the subtle aromas during a tasting. You can browse 7 tasting venues in Florence, South Carolina, with 6 listed with direct contact details to confirm dress code policies.

What to wear on a wine tour?

Dress in comfortable layers and wear closed-toe flat shoes suitable for cellar floors and outdoor vineyard walking. Bring a light jacket or sweater, as wine cellars are kept cool year-round. Check out 7 wine tour providers in Florence, South Carolina, including 6 that offer phone assistance for tour planning.