Of the 3 wineries listed in Mesilla, 3 give a phone number, 1 publishes opening hours and 3 have a website. No national chains here — every winery on this page is independent. The nearest bigger selection is Las Cruces with 5.
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Heart of the Desert - Historic Mesilla
1701 Avenida de Mercado, Mesilla, NM 88005-8221
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Heart of the Desert Pistachios & Wines
2355 Calle de Guadalupe, Mesilla, NM 88046-9015
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Vintage Wines
2461 Calle de Principal, Mesilla, NM 88046
Sat 10-4pm
More wineries within 30 miles of Mesilla
Only 3 wineries listed in Mesilla itself, so here are the closest ones in nearby towns. Distance is straight-line from Mesilla.
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D.H. Lescombes Winery & Bistro
0.4 mi · 1720 Avenida de Mesilla, Las Cruces, NM 88005-4056
Mon-Thu 11-9pm, Fri-Sat 11-10pm, Sun 11-8pm
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Luna Rossa Winery and Pizzeria
0.7 mi · 1321 Avenida de Mesilla, Las Cruces, NM 88005-3904
Mon-Sat 10-6pm, Sun 12-6pm
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Amaro Winery
2.1 mi · 402 S Melendres St, Las Cruces, NM 88005-2833
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Rio Grande Winery
3.5 mi · 5321 N Highway 28, Las Cruces, NM 88005-6231
Wed-Thu 2-9pm, Fri 12-10pm, Sat 11-10pm
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San Miguel Estate Vineyards & Winery
9.6 mi · 19560 NM 28, La Mesa, NM 88058
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Sombra Antigua Vineyard and Winery
18.7 mi · 430 La Vina Rd, Anthony, NM 88021-8535
Guides for winery shoppers
All guides
OwningThe Ultimate Guide to Charcuterie Boards: Styling, Pairings, and Recipes
Learn how to build balanced charcuterie and cheese boards, from festive holiday trees and brunch platters to portable grazing cups and effortless wine pairings.
OwningCrystal Wine Glassware Guide: Types, Brands, Care, and Stemless Styles
A practical guide to selecting, maintaining, and understanding crystal wine glassware, covering traditional stems, modern tumblers, sparkling vessels, and mineral compositions.
BuyingUnderstanding Bold Reds: Dry Wines, Tannin Profiles, and Old Vine Zinfandels
This guide breaks down what makes red wine dry, how tannins shape mouthfeel, what defines a full-bodied Cabernet, and why old vine Zinfandel earns its distinct reputation.
New Mexico statewide, by feature
- Wineries with Tastings in New Mexico38
- Winery Tours in New Mexico19
- Wineries with Food in New Mexico18
- Wineries with Outdoor Seating in New Mexico15
- Wineries and Tasting Rooms Offering Wine Tastings in New Mexico15
Nearby in New Mexico
Good to know about wineries in Mesilla
How many wineries are there in Mesilla?
We list 3 wineries in Mesilla with addresses, and 3 of them with a phone number.
What's the surest way to check hours in Mesilla?
Call ahead — 3 of the 3 wineries here list a number. Hours at independent wineries shift with seasons and staffing, so a phone call beats any listing, including ours.
Which wineries near Mesilla do tastings?
3 of 3 offer tastings.
What to wear wine tasting?
Smart casual attire is recommended, such as dark clothing to avoid stain visibility and comfortable flat shoes for walking on gravel or lawns. Avoid heavy perfumes as they interfere with the subtle aromas during a tasting. You can browse 3 tasting venues in Mesilla, New Mexico, with 3 listed with direct contact details to confirm dress code policies.